AN3-CA(人子宮內(nèi)膜腺癌細(xì)胞)
CBP60663
                       
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                | I. General information | |
| Synonyms: | AN3-CA | 
| Species: | Homo sapiens, human | 
| Tissue: | uterus; endometrium | 
| Disease: | adenocarcinoma | 
| Gender: | Caucasian,female,55years | 
| Morphology: | epithelial | 
| Growth Mode: | adherent | 
| Doubling Time: | 32 hrs | 
| DNA Profile: | Amelogenin: X CSF1PO: 12,14,15 D13S317: 12,14 D16S539: 10,14 D5S818: 11,14 D7S820: 7,10,7.1 THO1: 10,9.3 TPOX: 8,10 vWA: 14,20 Our Cell Line Authentication Service  | 
		
| Culture Medium: | 
				 MEM + 10% FBS+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) AN3-CA完全培養(yǎng)基,# CBP60663M  | 
		
| Cryopreservation medium: | 90%FBS+10%DMSO | 
| Antigen Expression: | Culture medium, 95%; DMSO, 5% | 
| Tumor Formation: | Yes, in nude mice,Yes, in the cheek pouch of cortisone treated hamsters | 
| Comments: | The cells exhibit ion transport activities consistent with cystic fibrosis and express the product of the CF gene (cystic fibrosis transmembrane regulator, CFTR).CFPAC-1 cells show no effect of cAMP agonists, adenyl cyclase stimulators or phosphodiesterase inhibitors on Cl- flux, but do respond to Ca++ ionophores with increase Cl- efflux. The cells have the most common form of the CF mutation, deletion of three nucleotides resulting in the absence of phenylalanine at position 508.CFPAC-1 cells have epithelial morphology and polarization with apical microvilli, tight junctions and gap junctions. For more information, please contact us (4008-750-250).  |