TPOR(Ligand Dependent)/BaF3
CBP73266
                       
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                    產(chǎn)品描述
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                | I. Introduction | |
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				 Cell Line Name:  | 
			
				 TPOR(Ligand Dependent)/BaF3  | 
		
| 
				 Host Cell:  | 
			
				 Ba/F3  | 
		
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | 
| Freeze Medium: | 90% FBS+10% DMSO | 
| Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin+500nM Eltrombopag | 
| 
				 Mycoplasma Status:  | 
			
				 Negative  | 
		
| II. Background | |
| 
				 Thrombopoietin receptor (TPOR) is a cytokine receptor protein present on the cell surface. The activation of TPOR by thrombopoietin (TPO) (a glycoprotein hormone) triggers an intracellular cascade of megakaryocytopoiesis for the formation of platelets.  | 
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| III. Representative Data | |
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				 1. WB of TPOR(Ligand Dependent)/BaF3 
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				 2.Anti-proliferation assay 
 Figure 2. CTG Proliferation Assay of BaF3 TPOR Cells (C3), the EC50=34.1nM.  | 
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