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                | Introduction | |
| Description | 滋養(yǎng)層細(xì)胞表面抗原2(Trophoblast cell sur-face antigen 2, Trop2)是由染色體1p32上的基因腫瘤相關(guān)鈣通道傳感蛋白2(tumor-associated calcium signal transducer 2, TACSTD2)編碼的36 kDa跨膜蛋白。研究表明,Trop2在多種實(shí)體瘤中高表達(dá),包括胃癌(Gastric cancer, GC)、乳腺癌(Breast cancer, BC)和宮頸癌(Cervical cancer, CC)等,其能通過(guò)參與多種細(xì)胞內(nèi)信號(hào)通路,例如絲裂原活化蛋白激酶(Mitogen-activated protein kinases, MA-PKs)和磷脂酰肌醇3-激酶(Phospoinositide 3-kin-ases, PI3K)等信號(hào)通路,從而促進(jìn)腫瘤細(xì)胞的增殖、遷移和侵襲。因其在實(shí)體瘤中高表達(dá)且與患者預(yù)后不良顯著相關(guān),Trop2已經(jīng)成為癌癥治療非常有潛力的靶點(diǎn)。 | 
| Technical Data | |
| 切片厚度 | 5 μm | 
| 示例 | ![]()  | 
		
| IHC染色結(jié)果 | |
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| Product Information | |
| Intended Use | Research Use Only | 
| Unit Size | 1片/張 | 
| Storage | -25~ -15℃ | 
| Expiry | 36 months from the date of manufacture | 
            
